DR. WALTER BOTTJE
Physiologist
DR. WALTER BOTTJE
Physiologist
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DR. WALTER BOTTJE Physiologist |
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Dr. Bottje graduated with honors in 1976, receiving a B.S. degree in Zoology with a Chemistry minor from Eastern Illinois University. After receiving an M.S. from Southern Illinois University, he completed a Ph.D. at the University of Illinois prior to being hired at the University of Arkansas in 1985. Dr. Bottje developed a research program focused on antioxidants and toxicology with an NIH grant he received in 1987.
In 1995, Dr. Bottje became the Associate Director of
the Center of Excellence for Poultry Science (CEPS) with a 30% administrative
appointment. In June 2003, Dr. Bottje was named the Department Head and Director
of the Center of Excellence for Poultry Science. In 2008, Dr. Bottje stepped back into a research and teaching position with the Center.
Dr. Bottje's current research focus is on the role that mitochondria play in
the phenotypic expression of feed efficiency in broilers. This research
has been supported by grants from USDA-NRI and Cobb-Vantress, Inc. (Siloam Springs,
AR). Previous research emphasis was on the role of mitochondria in the
pathophysiology of ascites (pulmonary hypertension syndrome).
SIGNIFICANT PAPERS
Bottje, W. G. and G. E. Carstens, 2009. Association of mitochondrial function and feed efficiency in poultry and livestock species. J. Anim. Sci. 87:E48-E63.
Ojano-Dirain, C., N. B. Tinsley, T. Wing, M. Cooper, and W. Bottje, 2007. Membrane potential and hydrogen peroxide production in duodenal mitochondria in broilers chickens (Gallus gallus) with low and high feed efficiency. Comp. Biochem Physiol. 147:934-941
Ojano-Dirain, C.P, N.R. Pumford, M. Toyomizu and W. G. Bottje, 2007. Association of mitochondrial function and feed efficiency. J. Poultry Sci. 44:221-237.
K. Lassiter, M. Iqbal, N. R. Pumford, C. Ojano-Dirain, N. Tinsley, T. Wing, M. Cooper, and W. Bottje, 2006. Differential expression of mitochondrial and extra-mitochondrial proteins in lymphocytes of low and high feed efficient male broilers. Poultry Sci. 85:2251-2259.
Bottje, W., N. Pumford, C. Ojano-Dirain, M. Iqbal, and K. Lassiter, 2006. Feed efficiency and Mitochondrial Function. Poult. Sci. 85:8-14.
Ojano-Dirain, C., N.R. Pumford, M. Iqbal, T. Wing, and M. Cooper, W. G. Bottje, 2005. Biochemical evaluation of mitochondrial respiratory chain in duodenum of low and high feed efficient broilers, 2005. Poult. Sci. 84: 1926-1934.
Ojano-Dirain, C., M. Iqbal, D. Cawthon, S. Swonger, T. Wing, M. Cooper, and W. Bottje, 2004. Determination of mitochoncrial function and site-specific defects in electron transport in duodenal mitochondria in broilers with low and high feed efficiancy. Poultry Sci. 83:1394-1403.
Cawthon D, M Iqbal, J Brand, R McNew, and WG Bottje, 2004. Investigation of Proton Conductance in Liver Mitochondria of Broilers with Pulmonary Hypertension Syndrome. Poultry Sci. 83: 259-265.
Bottje W.B. , Z Tang, M Iqbal, D Cawthon, R Okimoto, T Wing,
M Cooper, 2002. Association of mitochondrial function with feed efficiency within
a single genetic line of male broilers. Poultry Sci. 81: 546-555.
Tang Z, M Iqbal, D Cawthon, and WG Bottje, 2002. Heart and muscle
mitochondrial dysfunction in pulmonary hypertension syndrome in broilers (Gallus
domesticus) Comp. Biochem. Physiol. 132:527-540.
Iqbal M, JD Freiburger, GF Erf, and WG Bottje, 2002. Immunohistochemical
Evidence of Cytochrome c Oxidase Subunit II Involvement in Pulmonary Hypertension
Syndrome (PHS) in Broilers. Poultry Sci. 81:1231-1235.
CONTACT INFORMATION
Dr. Walter Bottje
University of Arkansas
POSC 0-405
Fayetteville, AR 72701
Telephone: 479-575-2575
FAX: 479-575-3026
